THE RELATIONSHIP OF SIDE EFFECTS OF DEPO MEDROXY PROGESTERONE ACETATE (DMPA) INJECTIONS TO CONTINUATION OF CONTRACEPTIVE USE

Authors

  • Devi Fitriani Efendi Poltekkes Kemenkes Bandung image/svg+xml
  • Ferina Ferina Poltekkes Kemenkes Bandung
  • Neneng Widaningsih Poltekkes Kemenkes Bandung
  • Saur Sariaty Poltekkes Kemenkes Bandung

DOI:

https://doi.org/10.34035/jmrh.v2i2.1927

Keywords:

continuity, contraceptive use, DMPA, side effects

Abstract

Background: The increase in population is partly due to the high dropout rate of contraceptive use. The reason for many dropouts is due to side effects. Depo Medroxy Progesterone Acetate (DMPA), as the most popular contraceptive method in Indonesia, has been reported by most acceptors to experience adverse events in the first three months of use. This affects the continuity of contraceptive use. The purpose of this study was to determine the relationship between side effects of DMPA injections and the continuity of contraceptive use at the Ibrahim Adjie community health center.
Methods: The research method used was a cross sectional approach. The population was women of childbearing age aged 15-49 years at Puskesmas Ibrahim Adjie, with a sample size of 100 respondents. Consecutive sampling technique. Data analysis chi square test.
Results: The results of this study showed that DMPA family planning acceptors who experienced side effects were 64 respondents (64.0%), and those who chose to drop out were 47 respondents (47.0%). The side effects of DMPA family planning caused 44 respondents (44.0%) to drop out. There was a significant relationship between the incidence of side effects of DMPA injections and the continuity of contraceptive use, with a p-value of 0.001≤ 0.05.
Conclusion: Side effects of Depo Medroxy Progesterone Acetate (DMPA) injections caused the dropout rate. 

References

A.N, S. G., Utami, N. W., & Candrawati, E. (2018). Hubungan lama pemakaian alat kontrasepsi hormonal suntikan depo medroxy progesterone acetate (DMPA) dengan peningkatan berat badan akseptor Kb di Wilayah kerja Puskesmas Arjuno Kota Malang. Nursing News : Jurnal Ilmiah Keperawatan, 3(3), 687–694.

Affandi, B., Adriaansz, G., & Koesno, H. (2021). Buku Panduan Praktis Pelayanan Kontrasepsi (G. Adriaansz & H. Koesno (Eds.); 3rd ed.). Bina Pustaka Sarwono Prawihardjo.

Ariska, P., & Ulfa, I. N. (2016). FAKTOR PENYEBAB DROP OUT PESERTA KB SUNTIK 3 BULAN DI DESA SIDOKATON KECAMATAN KUDU KABUPATEN JOMBANG: Factors Cause Drop Out Of Participants Kb Injection 3 Months In The Village Sidokaton Kudu District District Jombang. Jurnal Ilmiah Kebidanan (Scientific Journal of Midwifery), 2(1 SE-), 20–26.

Badan Pusat Statistik Provinsi Jawa Barat. (n.d.).

Bado, A. R. (2024). Determinants of DMPA-SC self-care/self-injectable contraceptive uptake among modern contraceptive users in Burkina Faso: findings from the 2021 demographic and health survey. Frontiers in Global Women’s Health, 5(September), 1–9. https://doi.org/10.3389/fgwh.2024.1385446

BPS. (2017). Jumlah Pasangan Usia Subur dan Peserta KB Aktif Menurut Kabupaten/Kota di Provinsi Jawa Barat, 2017.

BPS. (2023, March). Angka Kelahiran Total / Total Fertility Rate (TFR) Menurut Provinsi, 1971-2020. BPS.

BPS. (2024, June). Population of Indonesia 2023.

Dinkes Kota Bandung. (2022). Profil Kesehatan Bandung. Dinas Kesehatan Kota Bandung, 1.

Dragoman, M. V., & Gaffield, M. E. (2016). The safety of subcutaneously administered depot medroxyprogesterone acetate (104 mg/0.65 mL): A systematic review. Contraception, 94(3), 202–215. https://doi.org/10.1016/j.contraception.2016.02.003

Evitasari, mayla, Kholisotin, K., & Agustin, Y. D. (2019). Pengaruh Efek Samping Penggunaan Kontrasepsi terhadap Kejadian Unmet Need di Wilayah Kerja Puskesmas Klabang Kabupaten Bondowoso. Al-Asalmiya Nursing, 8(1), 53–65.

Hartanto, H. (2020). Keluarga Berencana dan Kontrasepsi. Pustaka Sinar Harapan.

Lailatul. (2020). Analisis Karakteristik Wanita Usia Subur di Kota Surabaya. Dinas Kesehatan Kota Surabaya.

MacLachlan, E., Atuyambe, L. M., Millogo, T., Guiella, G., Yaro, S., Kasasa, S., Bukenya, J., Nyabigambo, A., Mubiru, F., Tumusiime, J., Onadja, Y., Zan, L. M., Goeum/Sanon, C., Kouanda, S., & Namagembe, A. (2018). Continuation of subcutaneous or intramuscular injectable contraception when administered by facility-based and community health workers: findings from a prospective cohort study in Burkina Faso and Uganda. Contraception, 98(5), 423–429. https://doi.org/10.1016/j.contraception.2018.08.007

Nurhayati, N., S, S., & Hamang, S. H. (2023). Depo Medroxyprogesterone Acetate (DMPA): Long-Term Effects on Menstrual Cycle Disorders. Indonesian Journal of Obstetrics and Gynecology, 11(2), 93–98. https://doi.org/10.32771/inajog.v11i2.1884

Paulus, M., Octamelia, M., & Johan, R. B. (2025). Hubungan Lama Penggunaan Kontrasepsi Suntik 3 Bulan Dengan Kejadian Amenorea Di Praktek Dokter Mandiri Dr Wita Marlina Malinau Kota. Jurnal Ilmu Kedokteran Dan Kesehatan, 11(12), 2238–2245. https://doi.org/10.33024/jikk.v11i12.18892

Rahayu, A., Noor, M. S., Rahman, F., & Putri, A. O. (2017). Buku Ajar Kesehatan Reproduksi Remaja & Lansia. Airlangga University Press.

Rajaraman, R., Vaithilingan, S., & Selvavinayagam, T. S. (2024). Acceptance, Adherence, and Side Effects of Depot Medroxyprogesterone Acetate: A Prospective Observational Study. Cureus, 16(4), 1–8. https://doi.org/10.7759/cureus.58700

Sari, I. P. (2020). Analisis kualitas pelayanan KB terhadap kelangsungan pemakaian alat kontrasepsi hormonal (pil & suntikan) di Indonesia : analisis data SDKI 2007 = The quality of family planning services analyze with continuity use of hormonal contraceptive (pills & injec. June, 0–1.

Silvia, Jayatmi, I., & Rini, A. septa. (2024). Hubungan Gangguan Pola Menstruasi, Nyeri Kepala, Dan Tekanan Darah Terhadap Efek Samping Kb Suntik 3 Bulan. 16–23.

Witczak, W., Kukulska, A., Szeliga, A., Podfigurna-Stopa, A., Niwczyk, O., & Meczekalsk, B. (2022). Multiple complications associated with prolonged depot medroxyprogesterone acetate treatment. Case report and mini-review of literature. Gynecological and Reproductive Endocrinology and Metabolism, 3(2–3), 107–111.

Downloads

Published

2025-12-23

Issue

Section

Articles